Thiamine deficiency results in downregulation of the GLAST glutamate transporter in cultured astrocytes

Keyphrases

• Thiamine Deficiency 100%
• Glutamate Transporter 1 (GLT-1) 100%
• Cultured Astrocytes 100%
• GLAST 100%
• D-aspartate 42%
• Glutamate 28%
• Group II Metabotropic Glutamate Receptors 28%
• Cellular Level 14%
• Astrocytic 14%
• Metabolic Function 14%
• Astrocytes 14%
• Phosphorylation 14%
• Receptor Agonist 14%
• Excitotoxic 14%
• Thiamine Diphosphate-dependent Enzymes 14%
• Kinetic Analysis 14%
• Vmax 14%
• Km Value 14%
• Uptake Behavior 14%
• Wernicke Encephalopathy 14%
• Thiamine 14%
• α-ketoglutarate (α-KG) 14%
• Transketolase 14%
• Decreased Activity 14%
• Pyrithiamine 14%
• Dehydrogenase 14%
• Immunoblotting 14%
• Glutamate Transport 14%
• Glutamate Receptor Activity 14%
• Thiamine Diphosphate 14%
• Protein Kinase C Inhibitor 14%
• DCG-IV 14%
• Transport Function 14%
• Uptake Inhibition 14%
• Selective Vulnerability 14%

Neuroscience

• Astrocyte 100%
• Glutamate Aspartate Transporter 100%
• Thiamine 100%
• Glutamic Acid 37%
• Aspartic Acid 37%
• Metabotropic Receptor 25%
• Thiamine Pyrophosphate 25%
• Metabotropic Glutamate Receptor 25%
• In Vivo 12%
• Protein Kinase C 12%
• Western Blot 12%
• Oxoglutarate Dehydrogenase 12%
• Wernicke's Encephalopathy 12%
• Glutamate Transporter 12%
• Transketolase 12%
• Pyrithiamine 12%
• Receptor Agonist 12%
• DCG-IV 12%

Pharmacology, Toxicology and Pharmaceutical Science

• Thiamine Deficiency 100%
• Excitatory Amino Acid Transporter 100%
• Aspartic Acid 42%
• Glutamic Acid 42%
• Thiamine Pyrophosphate 28%
• Disease 14%
• Oxoglutarate Dehydrogenase 14%
• Western Blot 14%
• Thiamine 14%
• Wernicke's Encephalopathy 14%
• Glutamate Transporter 14%
• Pyrithiamine 14%
• Metabotropic Receptor Agonist 14%
• Transketolase 14%
• 2 (2,3 Dicarboxycyclopropyl)glycine 14%
• Protein Kinase C Inhibitor 14%
• Metabotropic Receptor 14%