Abstract
In this study the effects of different pacing protocols on left ventricular (LV) torsion was evaluated over the full cardiac cycle. A systolic and diastolic series of Magnetic Resonance Imaging scans were combined and used to calculate the torsion of the LV. The asynchronous contraction resulting from ventricular pacing interferes with the temporal evolution of LV torsion. From these experiments we have shown that measuring torsion is an extremely sensitive indicator of the existence of ectopic excitation. The torsion of the left ventricle was investigated under three different protocols: 1) Right atrial pacing, 2) Right ventricular pacing and 3) Simultaneous pacing from the right ventricular apex and left ventricular base. The temporal evolution of torsion was determined from tagged magnetic resonance images and was evaluated over the full cardiac cycle. The peak twist Tmax for the RA paced heart was 11.09 (±3.54) degrees compared to 6.06 (±1.65) degrees and 6.09 (±0.68) degrees for the RV and Bi-V paced hearts respectively. While biventricular pacing has been shown to increase the synchrony of contraction, it does not preserve the normal physiological twist patterns of the heart.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 217-224 |
| Number of pages | 8 |
| Journal | Proceedings of SPIE - The International Society for Optical Engineering |
| Volume | 3978 |
| State | Published - 2000 |
| Externally published | Yes |
| Event | Medical Imaging 2000: Physiology and Function from Multidimensional Images - San Diego, CA, USA Duration: Feb 13 2000 → Feb 15 2000 |
All Science Journal Classification (ASJC) codes
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Computer Science Applications
- Applied Mathematics
- Electrical and Electronic Engineering