Two-oscillator model of ventilatory rhythmogenesis in the frog

Amitabha Bose, Timothy J. Lewis, Richard J.A. Wilson

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Frogs produce two distinct yet highly coordinated ventilatory behaviors, buccal and lung. Lung ventilation occurs in short episodes, interspersed with periods of buccal ventilation. Recent data suggests that two brainstem oscillators are involved in generating these behaviors, one primarily responsible for buccal ventilation, the other for lung. Here we use a modeling approach to demonstrate that the episodic pattern of lung ventilation might be an emergent property of the coupling between the oscillators, and may not require a perturbing input from another, as yet unidentified but previously postulated, neuronal oscillator.

Original languageEnglish (US)
Pages (from-to)751-757
Number of pages7
JournalNeurocomputing
Volume65-66
Issue numberSPEC. ISS.
DOIs
StatePublished - Jun 2005

All Science Journal Classification (ASJC) codes

  • Computer Science Applications
  • Cognitive Neuroscience
  • Artificial Intelligence

Keywords

  • Brainstem
  • Coupled oscillators
  • Respiration
  • Respiratory rhythm
  • Synaptic facilitation
  • Ventilation

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